Contract research
Contract research from construct to validated model
FuBio takes on defined development work for gene therapy, biologics and diagnostics programs: stable cell line engineering, targeted screening campaigns, vector design and development, and supply of validated host cell lines. Projects run against agreed milestones with a named project manager.
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Milestone-based delivery
Scope, deliverables and acceptance criteria are agreed before work starts.
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Single point of contact
One project manager coordinates construct design, production, analytics and reporting.
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Confidentiality first
Work is covered by a mutual non-disclosure agreement, with client data segregated from catalog data.
Capabilities
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Construct and vector design
Cassette design, codon optimization, cloning strategy and sequence verification.
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Cell line engineering
Lentiviral or targeted integration approaches, single-cell cloning and expression validation.
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High-throughput screening
Library-based capsid and promoter screening with sequencing readout.
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Analytical support
qPCR, western blot, flow cytometry and potency assay development to suit the program.
Platforms in this line
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Stable cell line development
FuBio develops stable cell lines for overexpression, knockdown and knockout work. Projects can stop at a validated polyclonal pool or continue...
- Target validation and mechanism of action studies
- Reporter cell lines for high-throughput screening
- Recombinant protein and antibody expression
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Targeted screening
When a standard vector does not reach the target tissue efficiently, capsid or promoter engineering is the practical route forward. FuBio runs...
- Improving tissue specificity of AAV or lentiviral vectors
- Reducing off-target transduction
- Promoter selection for cell-type-specific expression
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Vector development
FuBio develops vectors end to end: gene synthesis and cassette design, cloning and sequence verification, packaging, purification and functional...
- New construct development for gene delivery programs
- Promoter and regulatory element comparison
- Multi-cassette vector engineering
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Ready-to-use cell lines
A catalog of 145 validated cell lines covers packaging tool cells, tumor models, immune cells and expression hosts. Catalog lines ship from stock and...
- Vector production and titer determination
- Oncolytic virus cytotoxicity testing
- Immunology and cell therapy research
Need a specification or a quotation?
Send the vector, payload and scale you need. We reply with feasibility, lead time and price within one business day.