Engineered virus platform

Herpes simplex virus

Herpes simplex virus type 1 offers a large genome and a well-characterized replication cycle, which makes it suitable for oncolytic and gene delivery studies where a substantial payload capacity is required.

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  • Large payload capacity

    The HSV-1 genome accommodates multiple or large transgenes without loss of viability.

  • Immunomodulatory payloads

    GM-CSF-armed HSV-1 constructs for immune activation studies.

  • Fluorescent variants

    mCherry-labeled HSV-1 for tracking infection and spread in culture.

  • Propagation and release

    Amplification with titer determination and contamination testing.

Typical applications

  • Oncolytic HSV-1 mechanism of action studies
  • Immune activation and payload comparison
  • Neuronal gene delivery research
  • Viral spread tracking with fluorescent reporters

Specifications

Catalog constructs
Armed and reporter HSV-1 variants
Volume
1 mL
Promoter
Endogenous HSV-1 promoter
Custom engineering
Payload design and deletion strategy on request

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