Contract research
Targeted screening
When a standard vector does not reach the target tissue efficiently, capsid or promoter engineering is the practical route forward. FuBio runs library-based screening campaigns and reads them out by sequencing.
-
Capsid engineering
Random peptide display and directed evolution libraries for altered tropism and immune escape.
-
Promoter screening
Comparative evaluation of promoters for tissue or context-restricted expression.
-
Library scale
Libraries built to campaign size, with barcoded readout to quantify variant enrichment.
-
Sequencing readout
Next-generation sequencing of enriched pools with per-variant hit reporting.
Typical applications
- Improving tissue specificity of AAV or lentiviral vectors
- Reducing off-target transduction
- Promoter selection for cell-type-specific expression
- Capsid variant characterization
Specifications
- Delivery
- Custom project, milestone based
- Readout
- Next-generation sequencing of enriched libraries
- Verification
- Individual hit validation on request
- Turnaround
- Scoped after library design review
Others in CRO Services
-
Stable cell line development
FuBio develops stable cell lines for overexpression, knockdown and knockout work. Projects can stop at a...
-
Vector development
FuBio develops vectors end to end: gene synthesis and cassette design, cloning and sequence verification...
-
Ready-to-use cell lines
A catalog of 145 validated cell lines covers packaging tool cells, tumor models, immune cells and expression...
Need a specification or a quotation?
Send the vector, payload and scale you need. We reply with feasibility, lead time and price within one business day.