Engineered virus platform

Oncolytic adenovirus

Oncolytic adenoviruses are the most widely used oncolytic platform. FuBio supplies adenoviral constructs with tumor-selective promoter control and armed payloads, plus capsid-modified variants aimed at improving tumor cell uptake.

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  • Tumor-selective replication

    E1A/E1B expression placed under hTERT or other tumor-associated promoter control.

  • Armed payloads

    GM-CSF, ADP and combination payload designs available in catalog and custom constructs.

  • Capsid modification

    RGD-motif insertion to broaden receptor usage and enhance transduction of target cells.

  • Reporter options

    EGFP and mEGFP variants for direct monitoring of replication in culture and in vivo.

Typical applications

  • Tumor cell selectivity and cytotoxicity studies
  • Oncolytic virus and immunotherapy combination research
  • Payload efficacy comparison in preclinical models
  • Viral replication and biodistribution tracking

Specifications

Catalog constructs
14 vectors available from stock
Volume
1 mL
Promoters
hTERT, E1A endogenous (D24) and CMV-driven payload cassettes
Custom engineering
Payload and capsid design on request

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Need a specification or a quotation?

Send the vector, payload and scale you need. We reply with feasibility, lead time and price within one business day.

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